The effects of Androstenedione vs. DHEA supplementation in men. Androstenedione is a popular and widely used supplement among body builders and athletes. Dehydroepiandrosterone or DHEA is a well-known precursor to testosterone, as well as a special interest as an anti aging supplement. Both supplements have been criticized for their ineffectiveness or lack of proof. Androstenedione has become extremely popular since, once home run, king Mark Mc Gwire admitted to using it during his extremely popular home run race in 1998. The NFL, the International Olympic Committee and NHL have banned the use of it. Androstenedione is a natural precursor to testosterone. The adrenal glands and gonads produce Androstenedione. In the liver Androstenedione can be converted to testosterone and back depending on the need (1). The anabolic effects that testosterone displays are what is desusers desirerostenedione can also be converted to estrone, a predominantly female hormone (2). This conversion is responsible for many of the possible negative side effects. The recommended dosage of androstenedione is 25mg to 100mg daily. Most supplement companies have made claims that androstenedione can boost testosterone. There have been no studies done to date that show androstenedione boosts testosterone enough to achieve any anabolic effects. There have been many independent studies that claim a 211% to 337% raise in serum testosterone levels but only for a limited amount of time.
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