Trisomy 18
EDWARD’S SYNDROME Trisomy 18 Syndrome is a rare chromosomal disorder in which all or a critical region of chromosome 18 appears three times (trisomy) in the cells of the body. ... COMPLETE NAME Edward’s syndrome is one of the common names for the genetic disorder Trisomy 18. Other common names for Trisomy 18 include Trisomy E Syndrome and Trisomy 16-18. SYMPTOMS OF EDWARD’S SYNDROME There are various degrees of abnormalities depending on the percentage of cells which are have a trisomic chromosome 18. Some symptoms include: growth deficiency feeding and breathing difficulties mental retardation malformations of the head and facial area narrow eyelid folds underdeveloped or absent thumbs, rocker-bottom feet, webbed fingers and toes (in males) failure of the testes to descend into the scrotum kidney malformations structural heart defects, which can lead to potentially fatal complications during infancy and pregnancy GENETIC CAUSE OF THE CONDITION Edward’s Syndrome is the result of having a third copy of chromosome 18.